reaching for reason

I've been wondering if, during every moment that we rush through (or is it the moments that rush through us?) there is any chance that relinquishing our grasp...our hold, on any sense of control or thirst or hunger, without feeling an aching void. The Buddha taught that all life was Dukkha...suffering, and that all suffering was a direct result of grasping instincts and urges. This is very often a comforting thought to me; but not always. This is the variability of human mood, ephemeral and ubiquitous, and married to how I feel about me in this instant.